Brief Summary
This video discusses the challenges of quitting smoking and vaping, highlighting the low success rates of quitting cold turkey. It introduces clinical hypnosis as a powerful behavioral method, with the Reveri app as a readily accessible tool. The video also explores pharmacologic approaches like bupropion (Wellbutrin) and nicotine replacement therapy, emphasizing the importance of varying nicotine delivery methods to disrupt dopamine release patterns. Key takeaways include the effectiveness of clinical hypnosis, the potential of bupropion for increasing dopamine levels, and the strategic use of nicotine patches, gum, and nasal sprays to manage withdrawal symptoms.
- Quitting smoking or vaping cold turkey has a very low success rate (around 5%).
- Clinical hypnosis, especially through the Reveri app, shows promising results in smoking cessation.
- Pharmacologic options like bupropion (Wellbutrin) can help by increasing dopamine levels.
- Nicotine replacement therapy is more effective when using a combination of methods (patch, gum, nasal spray) to vary dopamine release.
Introduction: The Difficulty of Quitting Nicotine
The video starts by highlighting that quitting vaping is often harder than quitting cigarette smoking. It points out that only a tiny fraction, about 5%, of people who try to quit smoking cold turkey actually succeed. Even among those who do quit, a large percentage relapse within a year. The speaker stresses that despite these challenges, quitting is possible and discusses both behavioral and pharmacological methods to help.
Clinical Hypnosis with Dr. David Spiegel
The video introduces clinical hypnosis as a powerful method for quitting nicotine, referencing the work of Dr. David Spiegel at Stanford. Clinical hypnosis involves the patient directing their own brain changes towards a specific goal. Studies have shown that a single hypnosis session can lead to complete smoking cessation in a significant percentage of people. The Reveri app, developed by Dr. Spiegel, offers hypnosis scripts for smoking cessation, mirroring the approaches used in clinical settings.
Pharmacologic Approaches: Bupropion (Wellbutrin)
The discussion moves to pharmacologic approaches, highlighting bupropion (Wellbutrin) as a common option. Bupropion increases dopamine release and is used for both depression and smoking cessation. The speaker notes that while he is not a psychiatrist, he will explain how bupropion is typically used to alleviate withdrawal symptoms. He also cautions about potential side effects like increased seizure risk and contraindications for individuals with liver or renal disease. Bupropion can increase the success rate of quitting from 5% to around 20%.
Nicotine Replacement Therapy
The video explores nicotine replacement therapy, where nicotine itself is used to help people quit smoking or vaping. The most effective approach involves a combination of methods like nicotine patches, gum, and nasal sprays. Using these in sequence, such as one for a week and then switching, helps keep the dopamine system off balance. This prevents the brain from expecting a single pattern of dopamine release, which is crucial for managing cravings and withdrawal.
Strategic Use of Nicotine Replacement
The speaker explains the rationale behind using different nicotine replacement methods. Nicotine patches provide a steady dopamine release, while gum and nasal sprays offer varying absorption rates. This variability is key to disrupting the brain's expectation of dopamine levels, similar to the random intermittent rewards used in casinos. By keeping dopamine levels variable, nicotine replacement can help individuals overcome smoking or vaping addiction.

