0:00 When I was a little boy my father told me constantly, son you have to live each day to the fullest, treat each day as special, and as if it were your last because it goes fast. And of course at the time I was a kid I didn't believe him but for decades and two kids later I find myself telling my own sons the exact same thing treat each day special because it goes fast. Now since the beginning of human civilization we've all looked for the Fountain of Youth we want to slow down the aging process I didn't think I was going to age when I was a little boy but I have found myself aged as a man now, so we're all looking
0:51 for it. In America alone in the United States alone the anti-aging industry takes in over 50 billion dollars a year. We're all seeking the Fountain of Youth. My name is Dr. Ryan Shelton. A couple of decades ago as the human genome project was coming to a close scientists discovered an important enzyme called sirtuin which may help slow down the aging process when it's activated and I know you're looking for the fastest way from point A to point B. How do we slow down the aging process. There are multiple theories of aging and
1:43 multiple mechanisms through which aging takes place but I want to talk about sirtuin because it's a really key enzyme for the aging process it's a highly conserved enzyme meaning evolutionarily it's found in plants and ants and worms and giraffes and elephants and monkeys and humans it's highly conserved because it plays a key role in deciding which pathway your DNA or your genes are expressed and I'll get into that in just a moment remember sirtuin is an enzyme enzyme is a biological catalysts enzymes accelerate chemical reactions and sirtuin stands as a guardian of genome repair mechanisms
2:34 it regulates metabolism transcription of genes and stress resistance it stimulates autophagy decreases mating factors and maintains telomeres now autophagy is a degradation of intracellular proteins and organelles and membranes as a mechanism of repair and maintenance sort of like taking out the trash or recycling which is important and again there are two pathways that genes can be expressed one is growth and reproduction where cell replicates and produces other cells the other pathway is protection and maintenance and sirtuin pushes the genetic expression towards
3:26 protection and maintenance it also maintains telomeres telomeres are the caps or the ends of DNA and and science has shown that as telomeres shorten the aging process accelerates over expression of sirtuin or activation of sirtuin there's a 30% increase in lifespan deletion of the gene or the enzyme it results in a 50% decrease in lifespan and eliminates the increase in lifespan with the known restricted caloric intake so science again has has shown that restricting calories can lengthen life span and sirtuin mimics
4:17 caloric restriction sirtuin can trick the genes into thinking that they're getting less calories even when you're not certain is involved in glucose metabolism fat mobilization lipid metabolism vascular tone resistance to neuro degeneration circadian rhythms and of course the aging process now there are some natural substances that you can take to promote and increase the activity of certain resveratrol ice Anatol pterostilbene by certain melatonin and there are things that inhibit sirtuin increased caloric intake increased weight high blood sugar smoking all of these
5:08 decrease sirtuin activity so we want to activate sirtuin if we want to slow down the aging process there's a really cool website I encourage you to check out aging - map org and it's spelled the British Way of aging AG e ing - map org it talks about all of the influences and the consequences of aging a really cool website I encourage you to check out now I want to know what your anti-aging secrets are I'm honoured and impressed with your time and attention so that you can learn more about your health and your wellness but I want to know what
5:53 your experiences are for anti-aging process we've made some other videos about the aging process I encourage you to check out at Zenith labs we've actually created a supplement called longevity activator which contains a number of ingredients to help promote the activity of sirtuin we've got a website Zenithlabs.com, a Facebook page and Instagram page. I want you to subscribe to this page like it and share it with your friends and loved ones. I believe in the original meaning of the word doctor, docere, which is teacher. So I'm here to help you learn more about how to promote optimal health and wellness again. Thanks so much for your time and attention, my name is Dr. Ryan
6:42 Shelton.
